The defense is expected to go after the prosecution's key witness Andrew Young, a former Edwards' aide who helped hide Hunter, going on the road with her to keep her away from the press, even claiming paternity for his boss.
Edwards defense has argued that much of the money was solicited by Young and he used the scandal to enrich himself.
Among Edwards' witnesses will likely be his daughter Cate, who has been his most visible supporter throughout the trial.
Hunter is on Edwards' list of witnesses, but it's not clear whether she will be called. Her presence in the courtroom could be volatile.
It's not yet known whether Edwards will take the stand in his own defense.