NPA Senior Vice President of Scientific and Regulatory Affairs Dr. Cara Welch responds: "We strongly believe this meta-analysis is a limited depiction of the benefits of omega-3 fatty acids on cardiovascular health. For example, the authors admit their results don’t take into account that more pharmaceuticals are being prescribed for heart disease, which can camouflage the cardiovascular benefit of omega-3s. Consumers should not be misled by this article. There is a significant amount of evidence showing the positive effects omega-3 fatty acids have on cardiovascular disease. This is based on epidemiological and observational studies as well as clinical trials looking at a variety of cardiovascular disease outcomes. The American Heart Association recommends a diet high in omega-3s and supplementation for those who cannot get enough from their diet. NPA also recommends consumers get their nutrients from a well-balanced diet, but unfortunately, most don’t. Supplementation is a safe and effective way for consumers to be sure they gain the nutrients essential to living a healthy lifestyle."